With a score of 93 out of a possible 100 Messi tops the player ratings in video game FIFA 15, which is due for release in the UK on September 26.
To get debate among fans raging in advance, makers EA Sports released a countdown of the top 50 players on the newest instalment of the popular franchise.
Messi came out on top, beating Real Madrid star Ronaldo (92) by just a single mark on the scoring system. Bayern Munich and Holland winger Arjen Robben was third with a total of 90.
The ratings, which are based on performances in league and cup games over the past 365 days, determine what each virtual player is capable of when used on the game.
Paris Saint-Germain striker Zlatan Ibrahimovic and Bayern Munich goalkeeper Manuel Neuer are ranked fourth and fifth on the new game, despite sharing the same rating as Robben.
Barca duo Andres Iniesta and Luis Suarez – both of whom have been given a score of 89 – sit six and seventh, with Bayern Munich pair Bastian Schweinsteiger and Franck Ribery (both 88) are eighth and ninth respectively.
Chelsea winger Eden Hazard, who has earned himself an 88 rating over the last year, is the only Premier League player to make the top 10, pipping Manchester United’s Robin van Persie and Radamel Falcao.
FIFA 15 TOP 10 PLAYERS
1. Lionel Messi 93
2. Cristiano Ronaldo 92
3. Arjen Robben 90
4. Zlatan Ibrahimovic 90
5. Manuel Neuer 90
6. Andres Iniesta 89
7. Luis Suarez 89
8. Bastian Schweinsteiger 88
9. Franck Ribery 88
10. Eden Hazard 88